Miss de León made numerous films, including: Basta Ikaw (As Long As It's You) with Emma Alegre, Tingnan Natin (Let's Look at It) with Nida Blanca and Nestor de Villa, Tuloy ang Ligaya (Happiness Goes On) with Leroy Salvador and Nida Blanca. She garnered a Famas Award Best Actress nomination for her role as the abused woman gone mad in Kidlat Sa Baril in 1964