Harmon co-starred as Megan Helms in the slasher film Black Christmas (2006), Heather Dalton in the science fiction horror film Hollow Man 2 (2006), and as Jill Eikland in the action horror film Dead Rising: Endgame (2016). In 2010, she won a Leo Award for Best Performance in a Music, Comedy, or Variety Program or Series for her role in the television pilot Wolf Canyon