Vrána, born to Czech parents in Norway, moved to Canada at age four. He made his feature-film debut in Canadian filmmaker David Cronenberg's Shivers. Vrána has appeared in television shows and films, including The New Avengers, The Littlest Hobo, Choices, Spearfield's Daughter, The Kiss, War of the Worlds, After Amy, All Souls, Friday the 13th: the Series, Windsor Protocol, Lobby, Highlander III: The Sorcerer, Sirens, All Souls, Mom P
I., The Hitchhiker, Press Run, Waking the Dead, Varian's War, Pachamama, and The Blue Man.